Normal High Energy Phosphate Ratios in “Stunned” Human Myocardium
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چکیده
منابع مشابه
Decreased high-energy phosphate ratios in the myocardium of men with diabetes mellitus type I.
AIMS/HYPOTHESIS To investigate whether alterations in high-energy phosphates occur in the myocardium of persons with diabetes mellitus type I. Microvascular abnormalities and dysfunction via thickening of the basement membrane are known to occur in diabetic patients. Myocardial high-energy phosphates have been shown to be reduced by ischemia, and alterations of the cardiac metabolism are the pr...
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Recent studies have shown that myocardial oxygen consumption does not proportionally decrease with the deterioration of contractile function in stunned myocardium. To investigate this disproportion, we studied the end-systolic pressure-volume relation and the relation between oxygen consumption per beat (Vo2) and systolic pressure-volume area (PVA, a measure of total mechanical energy) in stunn...
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Background. The main objective of the present study was to determine the role of adenosine in the development of myocardial stunning following multiple, brief periods of coronary artery occlusion as well as the subtype of adenosine receptor (A1 or A2) involved. A second objective was to determine if there was an interaction between the adenosine A1 receptor and the ATP-dependent K channel (KATP...
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A74-year-old woman was admitted for evaluation of chest pain. She had fallen and hit her head 4 days before her admission and had lost consciousness. Her chest pain had begun immediately after this event. An ECG on admission revealed abnormal Q waves and ST-segment elevation (Figure 1A). Her plasma creatine phosphokinase level was significantly elevated (386 IU/L), with an increase in MB isozym...
متن کاملHigh-energy phosphate concentrations in dog myocardium during stress.
BOERTH, ROBERT C.,JAMES W. COVELL, SHIRLEY C. SEAGREN, AND PETER E. POOL. High-energy phosphate concentrations in dog myocardium during str~s. Am. J. Physiol. 216(5): I. 103-l 106. I969.-The effects of increased cardiac workload on myocardial high-energy phosphate concentrations were examined in six dogs. Concentrations of creatine phosphate (CP) and adenosine triphosphate (ATP) were determined...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1997
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(97)00306-9